AtaGenix Laboratories
Single B cell rabbit monoclonal antibody technology amplifies antibody genes via PCR and produces antibodies through recombinant expression, delivering high-affinity, specific, and diverse antibodies. This method avoids clone loss, improves success rates for challenging antigens like PTMs, and is more efficient than traditional hybridoma techniques, ensuring faster, reliable results.
Why Choose Rabbit Single B Cell Technology? Rabbits’ unique immune system and larger spleens enable greater antibody diversity, higher affinity, and better recognition of PTMs and small molecules. Their simpler, stable IgG structures and natural light-heavy chain pairing make them ideal for advanced antibody development.
One-Week Delivery
Expertise in sequencing and expression ensures rapid turnaround
Enhanced 5' Accuracy
Ensures precise sequencing at the critical 5' region for optimal results
Pseudogene Exclusion
Eliminates pseudogene interference, guaranteeing reliable antibody gene analysis
AtaGenix's Single B Cell Technology workflow begins with rabbit immunization to generate antigen-specific B cells, followed by the isolation of PBMCs or splenocytes. Using advanced flow cytometry, Single B cells are precisely sorted, and antibody genes are amplified via RT-PCR. These genes are then recombinantly expressed and validated for high specificity and affinity. With its proprietary Xten™ Mab platform, AtaGenix ensures rapid, efficient, and precise production of high-quality rabbit monoclonal antibodies, meeting the demands for rare or low-quantity antigens in both research and diagnostic applications.