XtenCHO™ High-Density Transient Expression System Services

Service Overview
XtenCHO™ is a high-efficiency transient transfection CHO cell expression system independently developed by AtaGenix. Designed for high-density protein and antibody expression, this system achieves high expression levels (typically 200-400 mg/L, with some antibodies reaching up to 1 g/L). With a simplified process, it is particularly well-suited for high-throughput antibody expression needs.

Service Advantages

1. Advanced CHO Cell Line: The XtenCHO™ cell line is genetically engineered and optimized by AtaGenix. Combined with specialized vectors, it increases the copy number of the expression vector within cells and extends plasmid retention time, enabling high-level and stable gene expression.

2. Efficient Transfection Methods and Cultivation Models: The XtenCHO™ system enhances traditional CHO cell transfection methods by employing innovative high-density transfection technology and optimized cell culture protocols. This significantly improves post-transfection cell viability, extending cell survival from the conventional 6-7 days to 10-14 days, further boosting target protein yield.

3. Significant Cost Advantages: The XtenCHO™ system uses cost-optimized transfection reagents, culture media, and feed supplements. Compared to commonly available cationic lipid-based transfection reagents and CHO transient expression media, it offers substantial cost savings. This makes it highly suitable for industrial production, demonstrating excellent cost-effectiveness in large-scale recombinant protein manufacturing.

Service Workflow