普健生物(武汉)科技有限公司(AtaGenix)

Anti IL6 polyclonal antibody

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ATP165
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产品名(Product Name)icon
Anti IL6 polyclonal antibody
货号(Catalog No.)icon
ATP165
种类(Category)icon
Primary antibody
宿主(Host)icon
Rabbit
反应种属(Species specificity)icon
Human,other species was not test
应用实验(Tested applications)icon
WB:1:2000~1:8000,ICC:1:50~200,IHC:1:50~100
克隆性(Clonality)icon
Polyclonal
偶连物(Conjugation)icon
Unconjugated
免疫原(Immunogen)icon
Recombinant protein of human IL6(Val30-Met212).
别名icon
Interleukin-6,IFNB2,CDF,Hybridoma growth factor,IFN-beta-2,BSF-2,CTL differentiation factor,IL6,Interferon beta-2,B-cell stimulatory factor 2,IL-6
Uniprot IDicon
P05231
状态(Form)icon
Liquid
储存溶液(Buffer)icon
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
存放条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
浓度(Concentration)icon
0.36mg/ml
亚型(Isotype)icon
IgG
分子量(MW)icon
24kDa
纯化方式(Purity)icon
Antigen affinity purification
WB,ICC,IHC
    PMID: 30995492,PMID: 30995492,PMID: 30995492,PMID: 11080265
    Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

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