普健生物（武汉）科技有限公司（AtaGenix）
Anti IL6 mouse monoclonal antibody (35D11)
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产品名（Product Name）icon
Anti IL6 mouse monoclonal antibody (35D11)
货号（Catalog No.）icon
ATMA10092Mo
种类（Category）icon
Primary antibody
宿主（Host）icon
Mouse
反应种属（Species specificity）icon
Homo sapiens (Human)
克隆性（Clonality）icon
Monoclonal
克隆编号（Clone No.）icon
35D11
偶连物（Conjugation）icon
Unconjugated
免疫原（Immunogen）icon
Recombinant protein of human interleukin-6
别名icon
IL6,IFNB2
Uniprot IDicon
P05231
Noteicon
For research use only .
状态（Form）icon
Liquid
储存溶液（Buffer）icon
PBS, pH7.4
存放条件（Storage）icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
浓度（Concentration）icon
2.59mg/ml
亚型（Isotype）icon
IgG1
分子量（MW）icon
24kDa
纯化方式（Purity）icon
Protein G purified from mice ascites
PMID: 30995492,PMID: 15124018,PMID: 17075861,PMID: 20823453
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
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