普健生物(武汉)科技有限公司(AtaGenix)

Anti IL6 mouse monoclonal antibody

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ATMA10132Mo
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产品名(Product Name)icon
Anti IL6 mouse monoclonal antibody
货号(Catalog No.)icon
ATMA10132Mo
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
Mus musculus (Mouse)
克隆性(Clonality)icon
Monoclonal
克隆编号(Clone No.)icon
10-H1-F12
偶连物(Conjugation)icon
Unconjugated
免疫原(Immunogen)icon
Recombinant protein of mouse IL6
别名icon
IL6,IFNB2
Uniprot IDicon
P08505
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
存放条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
浓度(Concentration)icon
0.5mg/ml
亚型(Isotype)icon
IgG1
分子量(MW)icon
24kDa
纯化方式(Purity)icon
Protein G purified from mice ascites
ELISA
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

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