普健生物（武汉）科技有限公司（AtaGenix）
Anti 2019-nCoV S Protein RBD polyclonal antibody
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- 产品信息（Product Details）
- 参考文献
- 如何订购
- 说明书
产品概述（Summary）icon
产品名称（Product name）
Anti 2019-nCoV S Protein RBD polyclonal antibody
货号（Catalog#）
ATP248
描述（description）
Produced in rat immunized with purified,Recombinant SARS-CoV-2 S Protein RBD
Accession #
P0DTC2
别名（Alternative names)
S glycoprotein,E2,Peplomer protein,Spike protein S1
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -93 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -93 °C for twelve months from the date of receipt.
特异性（Spcificty）
Recognizes SARS-CoV-2 S Protein RBD
亚型（Isotype）
IgG
宿主（Host）
Rat
克隆性（Clonality）
Polyclonal
偶连物（Conjugation）
Unconjugate
种属反应性（Species reactivity）
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
应用实验（Tested applications）
Elisa
免疫原（Immunogen）
Recombinant SARS-CoV-2 S Protein RBD(Thr333-Pro527)
背景（Background）icon
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
产品性能（ Product performance）icon
状态（Form）
Liquid
储存溶液（Buffer）
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度（Concentration）
0.51mg/ml
分子量（MW）
141kDa
应用(Application)icon
应用实验及稀释比例（Dilution Range）
Elisa:1:4000~1:8000
产品实验图片（Tested Picture）icon
Noteicon
For research use only .
PubMed:32142651, PubMed:32075877, PubMed:32155444, PubMed:32362314
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