英文全称
Recombinant Human CILK1 protein
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白构建(Construction)
A DNA sequence encoding the human CILK1 (Met1-Gln277) was fused with His tag
Accession #
Q9UPZ9
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
预测分子量(Predicted Molecular Mass)
32.1 kDa
制剂(Formulation)
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景介绍
Required for ciliogenesis. Phosphorylates KIF3A. Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips . May play a key role in the development of multiple organ systems and particularly in cardiac development. Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity .
分子别名(Alternative Names)
Serine/threonine-protein kinase ICK,Ciliogenesis associated kinase 1,Intestinal cell kinase,hICK,Laryngeal cancer kinase 2,LCK2,MAK-related kinase,MRK.