英文全称
Recombinant Human IGF2BP3 protein
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白构建(Construction)
A DNA sequence encoding the human IGF2BP3 (Asn2-Ile343) was fused with His tag
Accession #
O00425
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
预测分子量(Predicted Molecular Mass)
40.12 kDa
制剂(Formulation)
lyophilized.Lyophilized from PBS pH7.5,0.02%NLS,1mM EDTA,4%trehalose,1% mannitol.
运输方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Reconstitute in sterile water for a stock solution.
背景介绍
RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.
分子别名(Alternative Names)
Insulin-like growth factor 2 mRNA-binding protein 3,IGF2 mRNA-binding protein 3,IMP-3,IGF-II mRNA-binding protein 3,KH domain-containing protein overexpressed in cancer,hKOC,VICKZ family member 3.