英文全称
Recombinant Human TRADD protein
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白构建(Construction)
A DNA sequence encoding the human TRADD (Met61-Leu297) was fused with His tag
Accession #
Q15628
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
预测分子量(Predicted Molecular Mass)
28.63 kDa
制剂(Formulation)
Lyophilized.Lyophilized from PBS pH7.4,0.02%NLS,1mM EDTA, 4%trehalose,1% mannitol.
运输方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Reconstitute in sterile water for a stock solution.
背景介绍
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
分子别名(Alternative Names)
Tumor necrosis factor receptor type 1-associated DEATH domain protein,TNFR1-associated DEATH domain protein,TNFRSF1A-associated via death domain.