英文全称
Recombinant Human FLIP protein
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白构建(Construction)
A DNA sequence encoding the human FLIP (Asp31-Asn184) was fused with His tag
Accession #
O15519
表达宿主(Host)
E.coli
种属(Species)
Homo sapiens (Human)
预测分子量(Predicted Molecular Mass)
19.1 kDa
制剂(Formulation)
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
运输方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景介绍
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
分子别名(Alternative Names)
CASP8 and FADD-like apoptosis regulator,Caspase homolog,CASH,Caspase-eight-related protein,Casper,Caspase-like apoptosis regulatory protein,CLARP,Cellular FLICE-like inhibitory protein,c-FLIP,FADD-like antiapoptotic molecule 1,FLAME-1,Inhibitor of FLICE,I-FLICE,MACH-related inducer of toxicity,MRIT.