普健生物（武汉）科技有限公司（AtaGenix）
Recombinant Human MPO protein
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- 产品信息（Product Details）
- 如何订购
- 说明书
概述（Summary）icon
英文全称
Recombinant Human MPO protein
纯度（Purity）
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白构建（Construction）
A DNA sequence encoding the human MPO (Cys606-Ser745) was fused with His tag
Accession #
P05164
表达宿主（Host）
E.coli
种属（Species）
Homo sapiens (Human)
预测分子量（Predicted Molecular Mass）
16.83 kDa
制剂（Formulation）
Lyophilized.Lyophilized from PBS pH7.4，0.02%NLS,1mM EDTA, 4%trehalose，1% mannitol.
运输方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Reconstitute in sterile water for a stock solution.
电泳图（SDS-PAGE image）icon
背景（Background）icon
背景介绍
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction.Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands.Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has been used previously to quantify the number of neutrophils in tissue. MPO activity was found to be linearly related to the number of neutrophil cells.The MPO system plays an important role in the control of infections and the deletion of malignant cells. Nevertheless, alternations in the MPO system can lead to DNA damage and carcinogenesis. Polymorphisms in the MPO Gene have been associated with an increased expression of MPO and a higher risk for development of cancer.Myeloperoxidase (MPO) is one of the major target antigens of antineutrophil cytoplasmic autoantibodies (ANCA) found in patients with small-vessel vasculitis and pauci-immune necrotizing glomerulonephritis.Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) is an autoantibody that is frequently found in patients with vasculitides.
分子别名（Alternative Names）
Myeloperoxidase,MPO,Myeloperoxidase,89 kDa myeloperoxidase,84 kDa myeloperoxidase,Myeloperoxidase light chain,Myeloperoxidase heavy chain.
Noteicon
For research use only .
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