产品名称(Product name)
Recombinant Human ACE2 protein
货号(Catalog#)
ATMP02478HU
描述(description)
Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-His Tag
表达系统(Expression system)
Mammalian cells
种属(Species)
Homo sapiens (Human)
Accession #
NP_001358344.1 or Uniprot Q9BYF1
别名(Alternative names)
ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,Metalloprotease MPROT15
预测分子量(Predicted Molecular Mass)
86.8kDa
纯度(Purity)
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)
Please contact with the lab for this information
制剂(Formulation)
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式(Shipping)
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)
Please refer to the instraction in the hard copy of COA.
应用(Application)
Immunogen
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.