普健生物（武汉）科技有限公司（AtaGenix）
Anti MUC1 polyclonal antibody
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- 产品概述
- 产品性能
- 应用
- 产品实验图片
- 参考文献
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- 如何订购
- 说明书
产品名（Product Name）icon
Anti MUC1 polyclonal antibody
货号（Catalog No.）icon
ATP225
种类（Category）icon
Primary antibody
宿主（Host）icon
Rabbit
反应种属（Species specificity）icon
Human,other species was not test
应用实验（Tested applications）icon
Elisa:1:4000~1:8000,IHC:1:50~100
克隆性（Clonality）icon
Polyclonal
偶连物（Conjugation）icon
Unconjugated
免疫原（Immunogen）icon
Recombinant protein of human MUC1(Ser24-Pro146）
别名icon
MUC-1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,CA 15-3,Carcinoma-associated mucin,Episialin,H23AG,Krebs von den Lungen-6,KL-6,PEMT,Peanut-reactive urinary mucin,PUM,Polymorphic epithelial mucin,PEM,Tumor-associated epithelial membrane antigen,EMA,Tumor-associated mucin,CD227,Mucin-1 subunit alpha,MUC1-NT,MUC1-alpha,Mucin-1 subunit beta,MUC1-beta,MUC1-CT,PUM
Uniprot IDicon
P15941
Noteicon
For research use only .
状态（Form）icon
Liquid
储存溶液（Buffer）icon
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
存放条件（Storage）icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.
浓度（Concentration）icon
0.75mg/ml
亚型（Isotype）icon
IgG
分子量（MW）icon
123kDa
纯化方式（Purity）icon
Antigen affinity purification
Elisa,IHC
PMCID: PMC1727008,PMID: 9212228,PMID: 15513966,PMID: 14688481,PMID: 12441351,PMID: 12832415,
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
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