普健生物(武汉)科技有限公司(AtaGenix)

Anti TNF α mouse monoclonal antibody

  • 1
  • 2
  • 3
ATMA10008Mo
-
+
现货
加入购物车
收藏
  • 产品概述
  • 产品性能
  • 应用
  • 产品实验图片
  • 参考文献
  • 产品背景
  • 如何订购
  • 说明书
产品名(Product Name)icon
Anti TNF α mouse monoclonal antibody
货号(Catalog No.)icon
ATMA10008Mo
种类(Category)icon
Primary antibody
宿主(Host)icon
Mouse
反应种属(Species specificity)icon
Homo sapiens,other species was not test
应用实验(Tested applications)icon
IHC
克隆性(Clonality)icon
Monoclonal
克隆编号(Clone No.)icon
81-H-4
偶连物(Conjugation)icon
Unconjugate
免疫原(Immunogen)icon
Recombinant protein of full length human TNF alpha
别名icon
Tumor necrosis factor;TNF;Cachectin;Tumor necrosis factor ligand superfamily member 2
Uniprot IDicon
P01375
状态(Form)icon
Liquid
储存溶液(Buffer)icon
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
存放条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 4 °C for frequent use.
Store at -20 to -80 °C for twelve months from the date of receipt.
浓度(Concentration)icon
1mg/ml
亚型(Isotype)icon
IgG1
分子量(MW)icon
26 kDa
纯化方式(Purity)icon
Protein G purified from mice ascites
IHC:1:100~200
    PMID: 12794819,PMID: 16829952,PMID: 22517918,PMID: 23396208,PMID: 16829952
    TNF, as also known as TNF-alpha, or cachectin, is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is expressed as a 26 kDa membrane bound protein and is then cleaved by TNF-alpha converting enzyme (TACE) to release the soluble 17 kDa monomer, which forms homotrimers in circulation. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation.

    1搜索商品:关键字搜索;分类导航搜索;产品联系:手机/微信同号:15972188750,座机:027-65279366(推荐 !

    2产品选购:确定好产品信息与规格,向产品客服询问底价

    3提交订单:向客服提交收货人信息,选择送货方式,支付方式,发票信息

    4产品发货:发票随产品一起发送,耐心等待收货即可


    质量保证:

    所售产品均经过严格的质量检验,确保所供产品的技术指标与生产厂家的目录、说明书、质检报告上的描述一致,请放心选购。


    质量与免责说明:

    买方验收产品时,如发现产品短缺、不匹配、包装破损等情况,请保持产品原包装状态,并在收货七个工作日内,以书面方式向我司提出异议。逾期未提出异议视为合格。

    买方保管产品时,应按照产品标签、说明书所示保管条件保存,如系保管不当导致产品质量问题,恕不受理。

    买方使用产品时。如发现产品质量问题,应在使用初期提出,而非在使用完或快使用完时提出,以备我司回收产品,确认产品质量。如确属质量问题,我司负责调换或退货。发生索赔事宜,我司将在产品价格额度范围内酌情赔偿,恕不受理超出产品本身价值之部分。自收货之日起,超过三个月未反映产品问题,恕不退换。

    我司所提供的产品仅限于专业人士的科学研究使用,不得用于临床诊断或者治疗,若有单位或者个人擅自改变我司产品用途,我司不承担任何责任。