普健生物(武汉)科技有限公司(AtaGenix)

ZAP-70(PT2241) mouse Monoclonal Antibody

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ATA39769
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产品名(Product Name)icon
ZAP-70(PT2241) mouse Monoclonal Antibody
货号(Catalog No.)icon
ATA39769
种类(Category)icon
Primary antibodies
宿主(Host)icon
Mouse/IgG1, Kappa
反应种属(Species specificity)icon
Human
应用实验(Tested applications)icon
IHC-p,WB
克隆性(Clonality)icon
Monoclonal
偶连物(Conjugation)icon
Unconjugated
免疫原(Immunogen)icon
Synthesized peptide derived from human ZAP-70
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
存放条件(Storage)icon
-20°C/1 year
纯化方式(Purity)icon
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
IHC-p 1:100-500,WB 1:500-2000
zeta chain of T cell receptor associated protein kinase 70(ZAP70) Homo sapiens This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

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