p63 mouse Monoclonal Antibody(PT2253)

p63 mouse Monoclonal Antibody(PT2253)

ATA34978

Primary antibodies

Mouse/IgG1, Kappa

Human

IHC-p

Monoclonal

Unconjugated

Synthesized peptide derived from human p63

Liquid

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C/1 year

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

IHC-p 1:100-500

tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim

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