普健生物(武汉)科技有限公司(AtaGenix)

p63 mouse Monoclonal Antibody(PT2253)

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产品名(Product Name)icon
p63 mouse Monoclonal Antibody(PT2253)
货号(Catalog No.)icon
ATA34978
种类(Category)icon
Primary antibodies
宿主(Host)icon
Mouse/IgG1, Kappa
反应种属(Species specificity)icon
Human
应用实验(Tested applications)icon
IHC-p
克隆性(Clonality)icon
Monoclonal
偶连物(Conjugation)icon
Unconjugated
免疫原(Immunogen)icon
Synthesized peptide derived from human p63
状态(Form)icon
Liquid
储存溶液(Buffer)icon
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
存放条件(Storage)icon
-20°C/1 year
纯化方式(Purity)icon
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
IHC-p 1:100-500
tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim

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