Epithelial Membrane Antigen(MUC1) (ABT-EMA) mouse Monoclonal Antibody

Epithelial Membrane Antigen(MUC1) (ABT-EMA) mouse Monoclonal Antibody

ATA28768

Primary antibodies

Mouse/IgG2b, Kappa

Human

IHC-p,WB

Monoclonal

Unconjugated

Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1)

Liquid

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C/1 year

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

IHC-p 1:100-500，WB 1:500-2000

mucin 1, cell surface associated(MUC1) Homo sapiens This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp

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